diff --git a/doc/sphinx/compiling.rst b/doc/sphinx/compiling.rst
index 348ddbe76..bb68b84a0 100644
--- a/doc/sphinx/compiling.rst
+++ b/doc/sphinx/compiling.rst
@@ -201,6 +201,9 @@ OS X
 
       CC=clang CXX=clang++
 
+* The Accelerate framework provides optimized versions of BLAS and LAPACK, so
+  the ``blas_lapack_libs`` option should generally be left unspecified.
+
 Intel Compilers
 ---------------
 * Before compiling Cantera, you may need to set up the appropriate environment