diff --git a/include/cantera/Cantera.h b/include/cantera/Cantera.h
index 33e421886..1cd9d8d1b 100644
--- a/include/cantera/Cantera.h
+++ b/include/cantera/Cantera.h
@@ -1,6 +1,8 @@
 /**
  * @file Cantera.h
  *  Basic include file to be used in all Cantera application environments.
+ *  @deprecated To be removed in Cantera 2.2. Applications should include
+ *     relevant headers directly.
  */
 
 /*